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www.benisonmedia.com  ARTICLE  feed intake compared to the   4th week compared to other   performance and FCR when   Fig. 3: Effect of dietary supplementation with different fractions of FWP on FCR of broiler chickens [Values with   www.benisonmedia.com

          Think Grain Think Feed - Volume 11 | Issue 9 | July 2025
 Think Grain Think Feed - Volume 11 | Issue 9 | July 2025


 treatment groups (p < 0.05)
 control. This improved
        different superscripts differ significantly (p<0.05), Mean±SD, n=4].
 whey was combined with
 as shown in Fig. 3. While no
 probiotics. Kanza et al. (2019)
 efficiency is attributed to
 significant difference in FCR
 noted that whey protein
 FWP's superior nutritional
 profile, offering high-quality
 study period, the T1 group
 supplementation boosted
 protein, essential amino
 maintained the highest FCR
 acids, and branched-chain   was observed over the entire   concentrate (WPC)
 feed consumption, weight
 amino acids (BCAAs), known   (1.95) at the 6th week,   gain, and body weight,
 for their role in muscle   numerically higher than T2   though without significantly
 protein metabolism and   (1.78), T4 (1.67), and T3   affecting FCR. Ashour et al.
 overall growth. Bovine whey   (1.67). This higher FCR in the   (2020) demonstrated
 protein's balanced essential   control group was linked to   improved FCR in all WPC-fed
 amino acid composition,   its higher feed consumption.   broiler groups compared to
 enhanced digestibility, and   The lower FCR observed in   controls, with optimal results
 high biological value   FWP-fed groups is   at 0.20% and 0.25% WPC.
 contribute to this. Beyond   potentially due to the   While FWP generally
 providing amino acids, FWP's  satiety-inducing effects of   promote satiety, enhance
 bioactive peptides (2–20   whey-derived peptides,   growth performance, and
 amino acid residues) exert   leading to reduced overall   support overall health and
 antimicrobial, antioxidant,   feed intake.  productivity, a crucial point   broilers.  reduced serum triglyceride,   density lipoprotein (HDL),
 antihypertensive, and   FWPs offer multiple   of our study was to directly   Supplementation with   cholesterol, and total lipid   low-density lipoprotein
 immunomodulatory effects,   functional benefits beyond   evaluate fermented whey   fermented cheese whey   levels in broiler chickens,   (LDL), and very-low-density
 promoting intestinal health   those of typical prebiotics   peptides (FWPs) as a viable   fractions (FWP) significantly   while no significant effect   lipoprotein (VLDL) levels over
 and disease resistance,   and probiotics, which   alternative to antibiotics in   was observed on high-  the entire study period as
 thereby enhancing feed   primarily support gut   poultry. We found that FWPs,
 efficiency. The T4 group,   immunity. FWP contains   administered for a mere one
 specifically, showed   essential amino acids,   week (1 mL per day), yielded
 enhanced gut development   organic acids, minerals,   comparable effects on
 and accelerated muscle   vitamins, and bioactive whey   growth performance to a
 growth, resulting in the   peptides with antioxidant   conventional probiotic and
 highest observed body   and antidiabetic properties.   immunomodulator regimen
 weight gain. All FWP diet   This multi-faceted   maintained for 42 days. This
 groups demonstrated   functionality contributes to   striking efficiency
 increased feed consumption   enhanced immunity,   underscores not only the
 and body weight gain until   improved gut microflora, and   health benefits of FWP for
 the 6th week, with FWP diets   a better blood profile in the   broiler birds, but also
 proving more palatable than   long term.  significant potential
 the standard diet.   Similar studies support these   economic advantages for
 Importantly, the addition of   findings: Hilmi et al. (2018)   poultry farmers due to
 whey protein fractions did   reported that fermented   reduced administration
 not affect the mortality rate   cheese whey as a   duration. This aligns with the
 in any FWP treatment groups   nutraceutical significantly   broader consumer demand
 (T2, T3, T4). The >10 kDa   decreased feed consumption   for antibiotic-free poultry,
 FWP fraction (T4) particularly   and FCR in poultry, while   which offers a reduced risk of
 improved overall body   also increasing egg   antimicrobial-resistant (AMR)
 weight gain by 42 days of   production. While some   pathogens and improved gut
 age.  research, like Sugiharto et al.   health in the final product.
 Regarding Feed Conversion   (2019), found no significant   Future research will further
 Ratio (FCR), a key indicator of  impact of whey powder on   explore FWP's impact on
 feed quality and weight gain   broiler FCR, others, such as   body fat composition, meat
 efficiency, the control group   Samli et al. (2019) and Zarei   and egg quality, egg
 (T1) exhibited a significantly   et al. (2020), observed   production capacity, and
 higher average FCR at the   improved growth   meat protein content in



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