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www.benisonmedia.com ARTICLE Think Grain Think Feed - Volume 11 | Issue 9 | July 2025 Think Grain Think Feed - Volume 11 | Issue 9 | July 2025 of probiotics, prebiotics, and www.benisonmedia.com

inflammation that
postbiotics—ideally
compromises gut barrier
integrity (“leaky gut”) in
delivered through next-
poultry. Subclinical infections
GEH (Gastrointestinal
with Clostridium further
Environment
exacerbate epithelial generation technologies like
damage, causing villus Harmonization)—are
atrophy and apoptosis while emerging as promising
increasing tight junction solutions for ensuring
permeability—undermining optimal gut functionality and
mucosal defenses and performance under modern
predisposing flocks to production pressures.
secondary bacterial Understanding Biotics in
GUT
GUT to standard anticoccidials Nutrition
infections. Rising resistance
Livestock and Poultry
worsens Eimeria-induced
The concept of integrating
mucosal injury, impairing
nutrient absorption and “biotics”—namely prebiotics,
probiotics, postbiotics, and
causing wet litter issues. synbiotic—has emerged as a
HEALTH
HEALTH and management poultry nutrition. As the
Moreover, environmental
cornerstone in modern
stressors—heat,
industry moves away from
overcrowding, transport,
feed changes—interfere with antibiotic dependence due
to rising antimicrobial
mucin secretion and gut- resistance, the modulation of
brain axis signaling, gut microbiota offers a
promoting barrier disruption sustainable and effective
Harmonizing Poultry Gut Health: environmental stress—can and dysbiosis. Finally, rapid alternative for promoting
batch turnover limits time for
intestinal integrity and
impair gut function
microbial stabilization,
A Functional Biotic-Based throughout the bird's life. leading to inconsistent gut overall productivity.
Each biotic category offers a
Feed components such as
health and heightened cycle-
Strategy from Concept to Application mycotoxins, oxidized fats, to-cycle vulnerability. distinct yet complementary
function:
and anti-nutritional factors
These evolving challenges
· Prebiotics, such as MOS
(e.g., soy agglutinins) induce
Dr. Kalyani Sarode, Optima Life Sciences highlight the urgent need for and XOS, are fermentable
oxidative stress, alter advanced, holistic strategies
As the poultry industry continues its more susceptible to imbalances in gut microbiota, disrupt tight focused on intestinal oligosaccharides that fuel
shift toward sustainable, antibiotic- microbiota, leading to an increased junctions and mucin layers, resilience. Approaches beneficial microbes.
· Probiotics, like Bacillus
free production systems, managing prevalence of opportunistic pathogens and initiate low-grade involving a synergistic blend
gut health is becoming increasingly and chronic enteric conditions. subtilis, Bacillus clausii,
complex. Emerging challenges are Additionally, early-life gut Functional Profile of Key Probiotics in Poultry Gut Health
reshaping how nutritionists, development is receiving growing Oxygen
veterinarians, and producers approach attention. The first 7–10 days post- Strain Type Requirement GIT Target Functional Role
intestinal health. hatch represent a critical window for
Gram+ Spore-forming Produces antimicrobial metabolites,
One of the most critical issues is microbial colonization, immune Bacillus subtilis Aerobic Upper GIT
Bacterium supports gut barrier
microbial dysbiosis and leaky gut priming, and intestinal
Gram+ Spore-forming Facultative Modulates immunity, controls loose
diarrhea in the post-antibiotic era. morphogenesis. Any disruption during Bacillus clausii Whole GIT
With reduced reliance on antimicrobial this stage—whether due to poor Bacterium Anaerobe droppings
growth promoters, poultry flocks are brooding, inadequate nutrition, or Clostridium Gram+ Spore-forming Strict Anaerobe Cecum & Produces butyrate, combats C.
butyricum Bacterium Colon perfringens

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